It should be mentioned that the Stun Gun works all ALL types of enemies in the game except for Nightmares and Cystoids, so if you want, you can just stun a Typhon and whack them to death with the Wrench.

Disruptor Stun Gun: I'd strongly suggest this for dealing with corrupted Operators and Technopaths, both of which are enemies who have a tendency to do massive amounts of electronic damage and kill you quickly.

It's considerably overpowered, meaning that you can take down Phantoms, Weavers, and even Nightmares in less than two mags. The Golden Gun is an upgraded version of the Silenced Pistol that does considerably more damage and is all-around a better weapon.

Golden Gun: Can be obtained from Jada Marks' safe in the Crew Quarters by doing the 'Golden Gun' sidequest.

Extremely useful for fighting off Mimics and Phantoms, which are enemies you really don't need to waste your ammo on.

Wrench: You can pick this up as soon as you start the game.

GLOO Gun: Since you won't be able to repair control panels with spare parts or hack into terminals to activate grav shafts, the GLOO will be your main method of traversal in high places throughout Talos I and will add a neat little platforming angle to the game.

Even then, they're still pretty damn useful against the Typhon. You'll only be able to upgrade your weapons in the first slots of their attributes, meaning that you'll only be able to spend 4 weapon upgrade kits on each gun instead of maxing them out. I'd recommend the Artax Gen 1 chipset, as this will increase the longevity of your suit's boost capacity and floating time. You CAN use Psychoscope chipsets and suit chips, but only two at a time. It may be okay to install a few for a power-related achievement and load the save back to having no mods installed, but if you actively install a neuromod and continue with the game, you will NOT get the achievement during the final cutscene. You CANNOT install any neuromods, whether they're Typhon-based or Human-based. 'No Needles' is exactly what it sounds like. I would very strongly suggest doing this achievement on your last playthrough, as at this point you can easily know the layout of Talos I and get things done quickly and efficiently. The bad news is that you can't hack into terminals, increase your health capacity, use psionic powers, mimic into locked rooms, repair objects, or increase your inventory.

The good news is that this achievement isn't nearly as daunting as it seems.

Prey golden gun vs silenced pistol